(3S)-3-[4-[(5-BroMo-2-Chlorophenyl)Methyl]Phenoxy]Tetrahydro-furan

(3S)-3-[4-[(5-BroMo-2-Chlorophenyl)Methyl]Phenoxy]Tetrahydro-furan

CAS NO:915095-89-5

Usage:Empagliflozin Intermediates

Chemical Name	(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
Synonyms	Empagliflozin Impurity I; (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran;
Impurity	Empagliflozin Impurity I
CAS Number	915095-89-5
Molecular Formula	C₁₇H₁₆BrClO₂
Appearance	White to Off-White Solid
Melting Point	49-51°C
Molecular Weight	367.66
Storage	Refrigerator
Solubility	DMSO (Slightly), Methanol (Slightly)
Category	Building Blocks;
Applications	(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.

Handling and storage
Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electro-
static charge. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated
place. Containers which are opened must be carefully resealed and kept upright to prevent
leakage.
Specific end use(s): Laboratory chemicals, for scientific research and development only.
Application Empagliflozin intermediate