China 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane Manufacturers & Suppliers

Product Description

5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane

Usage:Dapagliflozin Intermediates

Chemical Name	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Synonyms	4-Bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene;
CAS Number	461432-23-5
Molecular Formula	C₁₅H₁₄BrClO
Appearance	White to Off-White Low-Melting Solid
Melting Point	41-43°C
Molecular Weight	325.63
Storage	-20°C Freezer
Solubility	Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
Category	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene is used as a reagent in the synthesis of Dapagliflozin (D185370); a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes .

Hazards identification

Classification of the substance or mixture:
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Acute toxicity,oral (Category 4), H302
2.2. GHSLabelelements,includingprecautionarystatements:
Pictograms
Signal word Warning Hazard statement(s).
H302 Harmful if swallowed
Precautionary statement(s).
P264 Wash thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312+P330 If swallowed: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse
mouth.
P501 Dispose of contents/container to an approved waste disposal plant.

Handling and storage
Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electro-
static charge. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent
leakage.
Specific end use(s): Laboratory chemicals, for scientific research and development only.
Application Dapagliflozin intermediate

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