China (3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One Manufacturers & Suppliers

Product Description

(3R,4S,5R,6R)-3,4,5-Tris(TriMethylsilyloxy)-6-(TriMethylsilyloxy)Methyl)Tetrahydro-2H-Pyran-2-One

CAS NO:32384-65-9

Usage:Dapagliflozin Intermediates

Chemical Name	2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone
Synonyms	(3R,4S,5R,6R)-3,4,5-Tri[(trimethylsilyl)oxy]-6-[[(Trimethylsilyl)oxy]methyl]tetrahydro-2H-pyran-2-one;
CAS Number	32384-65-9
Molecular Formula	C₁₈H₄₂O₆Si₄
Appearance	Colourless to Pale Yellow Oil
Melting Point	N/A
Molecular Weight	466.86
Storage	Refrigerator
Solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.

HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Storage conditions: Refrigerator
Application Empagliflozin intermediate

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