China Boc-(R)-3-AMino-4-(2,4,5-Trifluorophenyl)Butanoic Acid Manufacturers & Suppliers

Product Description

Boc-(R)-3-AMino-4-(2,4,5-Trifluorophenyl)Butanoic Acid

CAS NO:486460-00-8. Usage:Sitagliptin Intermediates

Chemical Name	(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
Synonyms	(βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-benzenebutanoic Acid; 3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (3R)-3-[N-(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (R)-3-(((tert-Butoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butyric Acid; (R)-3-[(tert-Butyloxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid;(R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid;
CAS Number	486460-00-8
Molecular Formula	C₁₅H₁₈F₃NO₄
Appearance	White to Off-White Solid
Melting Point	129-130°C
Molecular Weight	333.3
Storage	Refrigerator
Solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig
Category	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.