Product Name:Ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-Oxo-4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]Pyridine-3-Carboxylate
CAS NO:503615-07-4
Formula: C22H22N4O4
Molecular Weight:406.43
Usage:Apixaban Intermediates
Ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-Oxo-4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]Pyridine-3-Carboxylate
CAS NO:503615-07-4
Molecular Formula
C₂₂H₂₂N₄O₄
Appearance
White to Off-White Solid
Molecular Weight
406.43
Storage
Refrigerator, Under inert atmosphere
Solubility
Chloroform (Slightly), DMF (Slightly)
Category
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications
Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Application Apixaban intermediate